|
High Blood Pressure and Kidneys
|
|
The kidneys are very important
in controlling blood pressure of a person, and blood pressure, in turn, can affect the health of
the kidneys. If you have high blood pressure, your kideys can be effected and you can have chronic
kidney disease i.e CKD.
How does high blood pressure destroy the
kidneys?
High blood pressure causes
thickening of kidney vessels. If the blood vessels in the kidneys are damaged, they may stop
removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then
raise blood pressure even more. High blood pressure is one of the leading causes of kidney
failure, also called end-stage renal disease (ESRD). Every year, high blood pressure causes more
than 25,000 new cases of kidney failure in the USA.
What are the signs and symptoms of chronic kidney
disease (CKD)?
If you have Kidney disease in
early stages, usually there are no symptoms. People may have CKD but not know it because they do
not feel sick. A person’s glomerular filtration rate (GFR) is a measure of how well the kidneys
are filtering wastes from the blood. GFR is measured by finding creatinine level in blood. The
result is called eGFR, the estimated GFR.
When muscle cells are breaked a
waste product is produced called as Creatinine. Healthy kidneys take creatinine out of the blood
and put it into the urine to leave the body. If you have kidney disease creatinine level rises
in blood as kidneys are unable to excreat this waste. An eGFR with a value below 60 milliliters
per minute (mL/min) suggests some kidney damage has occurred.
You may also find Proteinuria
in CKD, i.e protein in Urine. Healthy kidneys take wastes out of the blood but leave protein.
Defected or diseased kidneys may fail to separate a blood protein called albumin from the
wastes. In initial stages, only small amounts of albumin may leak into the urine, a condition
known as microalbuminuria. As with time kidneys are more affected, the amount of albumin and
other proteins in the urine increases, and the condition is called proteinuria. CKD is present
when more than 30 milligrams of albumin per gram of creatinine is released in urine, with or
without low eGFR.
How can you prevent kidney damage from high blood
pressure?
The National Heart, Lung, and Blood Institute (NHLBI), one of the
National Institutes of Health (NIH), recommends that people with CKD use whatever therapy is
necessary, including lifestyle changes, excercises and medicines, to keep their blood pressure
below 130/80.
Are you at risk of Kidney failure due to High
Blood presure?
If you have high blood pressure
you are at risk of developing kidney failure. African Americans, however, are more likely than
Caucasians to have high blood pressure and its related kidney problems even when their blood
pressure is only mildly elevated. Studies show that African Americans are six times more likely
than Caucasians to develop hypertension-related kidney failure.
If you have diabetes along with
high blood pressure you are more prone to develope kidney failure. Early management of high
blood pressure is especially important for African Americans with diabetes. The National
Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), also part of the NIH, sponsored
the African American Study of Kidney Disease and Hypertension (AASK) to find effective ways to
prevent high blood pressure and kidney failure in this population. The results, published in the
November 20, 2002, issue of the Journal of the American Medical Association, showed that an ACE
inhibitor was the most effective drug at slowing the progression of kidney disease in African
Americans. While ACE inhibitors help reduce the risk of CKD, they are less effective in
decreasing blood pressure among African Americans than in Caucasians.
|